Splenic arterial dissection and factor V Leiden mutation causing massive spleen infarction

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Splenic arterial dissection and factor V Leiden mutation causing massive spleen infarction.

A 48 year-old man was referred to emergency ward because of pain on the left side of the abdomen and low-grade fever, triggered by moderate physical exercise. He smoked 20 cig./day but denied hypertension, diabetes or dislipidemia. Physical examination was unremarkable. Serum biochemistry showed total cholesterol 255 mg/dL, LDL cholesterol 167 mg/dL, HDL cholesterol 35 mg/dL and triglycerides 2...

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Factor V Leiden Mutation Causing Thrombophilia

It has autosomal dominant inheritance and is the most common cause of inherited thrombophilia. FVL is the most prevalent thrombotic risk factor known in the Caucasian population (around 5%). [1] Heterozygotes have a three to five times increased risk of thrombosis. Homozygotes are much less common but have a much higher thrombotic risk, around eight times increased risk. It leads to a hypercoag...

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Factor V Leiden Mutation Causing Thrombophilia

It has autosomal dominant inheritance and is the most common cause of inherited thrombophilia. FVL is the most prevalent thrombotic risk factor known in the Caucasian population (around 5%). [1] Heterozygotes have a three to five times increased risk of thrombosis. Homozygotes are much less common but have a much higher thrombotic risk, around eight times increased risk. It leads to a hypercoag...

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Factor v leiden mutation in reocclusion after intra-arterial thrombolysis.

BACKGROUND AND PURPOSE Reocclusion of intracranial arteries after successful recanalization is associated with poor clinical outcome. The role of Factor V Leiden mutation in intracranial arterial thrombosis/rethrombosis is unclear. SUMMARY OF REPORT We report the case of a patient who developed recurrent reocclusions of the middle cerebral artery after intra-arterial thrombolysis for acute is...

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Background: Factor V Leiden, Prothrombin gene (G20210A) and MTHFR (C677T) polymorphism are the main biomarkers for evaluation of tendency for venous thromboembolism. We aimed to investigate the frequency of mutations in factor V Leiden, Prothrombin G20210A and MTHFR C677T and identify the genetic status for these mutations in patients with venous thrombosis. Methods: This study was carried out...

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ژورنال

عنوان ژورنال: Revista Española de Enfermedades Digestivas

سال: 2011

ISSN: 1130-0108

DOI: 10.4321/s1130-01082011000800014